Ethyl Pyruvate Ameliorates Endotoxin-Induced Corneal Inflammation

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Ethyl Pyruvate Ameliorates The Damage Induced by Cyclophosphamide on Adult Mice Testes

Objective Cyclophosphamide (CP) is a chemotherapy drug which causes deleterious effects on testicular tissue and increases free radicals in the body. The aim of this study is to investigate the protective effects of ethyl pyruvate (EP) on testicular improvement in CP treated animals. MaterialsAndMethods In this experimental study, 15 male mice (6-8 weeks) were divided into 3 groups. The control...

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ethyl pyruvate ameliorates the damage induced by cyclophosphamide on adult mice testes

objective: cyclophosphamide (cp) is a chemotherapy drug which causes deleterious effects on testicular tissue and increases free radicals in the body. the aim of this study is to investigate the protective effects of ethyl pyruvate (ep) on testicular improvement in cp treated animals. materials and methods: in this experimental study, 15 male mice (6-8 weeks) were divided into 3 groups. the con...

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Preventive effects of ethyl pyruvate on endotoxin-induced uveitis in rats.

PURPOSE Recent studies indicate that ethyl pyruvate (EP) exerts anti-inflammatory properties; however, the effect of EP on ocular inflammation is not known. The efficacy of EP in endotoxin-induced uveitis (EIU) in rats was investigated. METHODS EIU in Lewis rats was developed by the subcutaneous injection of lipopolysaccharide (LPS; 150 μg). EP (30 mg/kg body weight) or its carrier was inject...

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Ethyl pyruvate reduces mortality in an endotoxin-induced severe acute lung injury mouse model

BACKGROUND Ethyl pyruvate (EP) was recently identified as an experimental therapeutic agent in a wide variety of model systems for inflammation-mediated tissue and cellular injury. OBJECTIVE To evaluate the effect of ethyl EP on improving the survival in mice with LPS-induced acute lung injury (ALI). METHODS ALI was induced by administering lipopolysaccharide (LPS) intratracheally. The mice...

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Ethyl Pyruvate Ameliorates The Damage Induced by Cyclophosphamide on Adult Mice Testes.

BACKGROUND Cyclophosphamide (CP) is a chemotherapy drug which causes deleterious effects on testicular tissue and increases free radicals in the body. The aim of this study is to investigate the protective effects of ethyl pyruvate (EP) on testicular improvement in CP treated animals. MATERIALS AND METHODS In this experimental study, 15 male mice (6-8 weeks) were divided into 3 groups. The co...

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ژورنال

عنوان ژورنال: Investigative Opthalmology & Visual Science

سال: 2012

ISSN: 1552-5783

DOI: 10.1167/iovs.11-9266